Folium Psidium guajava extract

Folium Psidium guajava extract is extracted from Folium Psidium guajava used to make medicinal products and health foods. Fresh Folium Psidium guajava is often steeped for water or used directly in folk to support the treatment of symptoms related to the gastrointestinal tract such as: abdominal pain, loose stools, raw stools, food poisoning.

1. General introduction to medicinal herbs

Plant description

Guava, scientifically known as Psidium guajava, belongs to the family Peach Kim Nuong, is a perennial fruit tree. Guava is a root tree. Guava roots often go deep into the ground, have a special structure, adapt to many soil conditions. When the weather is hot and dry, the groundwater is deep, the roots of guava can grow up to 3-4 m or more to provide enough water for the plant. If the weather is rainy, guava roots will grow more branches close to the ground to avoid the tree being suffocated.

Guava is a woody, tall tree with many branches, 4-6 m high, 10 m high, maximum trunk diameter 30 cm. Stems are strong, strong, smooth, very few borers. When the guava body is old, the peel is often peeled off in patches. The new shell has a gray or green interior, which is also smooth. Young branches have 4 edges, when they are old, they will gradually round.

Leaves simple, opposite, without accompanying leaves. The leaf blade is oval, the upper surface of the leaf is darker, the petiole is rounded, about 5 – 10 cm long. Leaves whole, rounded margins, with a purplish-pink border extending to the petiole. Leaf veins are feathery, midrib is prominent on the underside. Petiole green, cylindrical, 1-1.3 cm long.

Flowers are large, hermaphroditic, growing in clusters of 2 or 3, rarely at the tips of branches but often in the axils of leaves. The petals are white, thin, and fall off easily when the flower blooms. Flowers cross-pollinate easily but can also self-pollinate.

The fruit is round, ovate or pear-shaped, 3 – 10 cm long, depending on the variety. The young pods are green, turn yellow when ripe, and the flesh is white, yellow or red. The intestines are white, yellow or red. Ripe fruit has a sweet or sour taste and has a characteristic aroma.

Guava has many seeds, yellow-brown polygonal shape, has a hard shell and is located in a white, pink, and red-yellow fleshy mass.

Distribution

Guava trees have been grown in tropical and subtropical regions around the world since the European occupation of the Americas.

Currently, guava is grown in many countries in Africa, South Asia, Southeast Asia, the Caribbean, subtropical North America, and Australia.

Through the process of cultivation and selection of varieties, guava varieties are now also very rich and diverse. In addition to the common guava (Psidium guajava) popular around the world, there are also special local guava varieties such as: buffalo guava, bo guava, and sage guava with large fruit but less sweet aroma; Fat guava, glove guava, peach guava, turmeric guava are small but sweet and very fragrant.

In Vietnam, the common guava tree (Psidium guajava) was introduced to be planted at an unknown time and it is grown all over the country from the coastal plain to the mountains with an altitude of about 1500 m or less.

Today, in addition to the normal guava variety, in Vietnam there are also new varieties of guava such as lo Xa Lo imported from China and seedless guava which have been popularized recently thanks to modern breeding technology.

Harvest

Leaves, buds, bark or roots of Folium Psidium guajava can be harvested all year round, while the fruit can only be harvested when ripe. After harvesting, wash and use directly or dry to use gradually

Uses of Folium Psidium Guajava

Folium Psidium guajava looks ordinary, but hidden deep inside is the value it brings into existence:

Cure diarrhea

Lower cholesterol

Limit diabetes

Losing weight

Fight against cancer

Cure colds and coughs

Reduce acne

Good for skin and hair

Good for teeth

Improve sleep quality

2. Folium Psidium guajava extract

(A) Extract Folium Psidium guajava with hot water at 90 – 98°C to make the extract:

Use fresh Folium Psidium guajava or you can dry Folium Psidium guajava to use. Leaves are broken, broken with a size of 1 – 10 mm, preferably 3 – 5 mm.

Solvents including water, ethanol and acetone can be used for extraction. If the extract is to be used in food, the best solution to use is water or a mixture of water-ethanol solvents. The mass of Folium Psidium guajava is 1, the volume of solvent used can be from 10-40, the best ratio is 15-25 parts of solvent/1 part Folium Psidium guajava. If less than 10 parts by mass solvent is used, the extraction efficiency is low; if the amount of solvent is more than 40 parts by mass, the efficiency of the concentration step decreases.

Folium Psidium guajava is extracted with a solvent at a temperature of 90-98%, preferably in the range of 93-97°C. If extraction at a temperature lower than 90°C, the extraction efficiency is not higher than 98°C, the value of extracted components is reduced and the amount of precipitate increases after dissolving in water or hot water. Time from 3 to 30 minutes.

(B) Concentrate the extract with Brix degree of 20 – 30

Folium Psidium guajava concentrate is extracted from step (A) to 20 – 30 degrees Brix, preferably between 23 – 28. When the concentrate has a Brix of less than 20, the enzymatic hydrolysis efficiency may be reduced; If the Brix degree exceeds 30, a large amount of precipitates may form in the Folium Psidium guajava extract. This concentration can be accomplished by means of an evaporator, preferably at 25–27°C under a vacuum of 0–48 kPa.

(C) Drying of concentrated extract

Products after stage (B) are freeze-dried to keep product quality. First freeze at – 20°C – 50°C, at least for 10 hours. From 35 to – 40°C for 15 – 30 hours is best. Following the freezing stage, the pressure is changed from 4 to 107 Pa and the water evaporates from the material from the solid state to the vapor state without going through the liquid state (sublimation). It is through this process that quality variations are minimized. At the end of this stage, about 95-98% of the water is separated from the material.

Spray drying can be used to spray concentrated Folium Psidium guajava solution after stage (B) into powder. However, the resulting powder has a strong oxidizing odor, and the taste is not delicious.

If you want the product to be in the form of granules, you can use a fluidized bed granulator, extruder, etc. and use binders in the granulation process such as pullulan, starch, dextrin, hydroxypropylmethyl cellulose, etc.

Folium Psidium guajava extract powder is stable in quality and can be stored for a long time. In addition, the powder has high solubility in water or hot water.

However, when stored for a long time, Folium Psidium guajava powder, polyphenols, tannins and other ingredients will create turbidity or precipitate the product, reduce product appearance, and affect consumer psychology. Therefore, it is possible to remove polyphenols by filtration through diatomite, by absorbing resins and by tannase degradation. However, some of these removal components are characteristic of Folium Psidium guajava, which should be considered when choosing a treatment method.

3. Folium Psidium guajava extract raw material information

This is a line of Folium Psidium guajava extract, which is prepared by Biogreen Pharmaceutical and Biotechnology Joint Stock Company from raw Folium Psidium guajava medicinal ingredients. On the most modern production lines and technology today, with strict production standards before being put on the market.

Product Name: Folium Psidium guajava extract

Description: Light green uniform fine powder

Dosage form: Powder, dried extract

Specification: 1 kg, 2 kg, 5 kg, 10 kg, 25 kg

Solubility: Well soluble in water

As suitable raw materials for dosage forms: nuggets, powders, effervescents, capsules, tablets, syrups

Taste: Bitter, slightly acrid, fragrant